A water Soluble Powder for Oral Use
Composition: Each 1 gm contains :
Erythromycin thiocuanate 115 mg a.i
Colistin sulphate 400 000 I.U
Erythromycin and Macrolides in general, act on the bacterial cell by inhibiting the protein synthesis, without affecting the nucleic acid synthesis. Erythromycin could inhibit the protein synthesis by settling on the fraction 50 S of bacterial ribosomes (Ribosomes being intra-cytoplamsic organites of cells responsible for the protein synthesis).
Erythromycin is above all active on Gram positive bacteria and also on some Gram negative as well as active against mycoplasma, bacteria and some large viruses and some helminthes.
Colistin has a broad spectrum bactericidal activity used in the treatment of intestinal infections caused by gram-negative bacteria (E.coli, Salmonella species, shigella, klebsiella, haemophilus and pseudomonas) in poultry, calves and other young animals. It has no toxic effect if given orally because it is poorly absorbed from the gastro-intestinal tract.
For the treatment of infections caused by sensitive gram positive and gram negative bacteria and mycoplasma such as CRD ,CRD complex ,coryza , infectious sinusitis ,synovitis and enteritis .
Colimycin is also recommended during stress conditions and positive vaccination in poultry, lambs and calves.
Doses and Administration:
Poultry: 1 gm per 1 liters of drinking water for 3-5 days
Calves & Lambs : 2 gm per 10 kg body weight daily for 3-5 days via drinking water or mixed with daily feed.
Withdrawal period: 2 days.
Store in dark place at a temperature below 30C.
100, 500 g and 1kg aluminum foil bag.
FOR VETERINARY USE ONLY