Composition:Each 1 ml contains:
Sulphaquinoxaline sodium 250 mg.
Sulphaquinoxaline is readily absorbed from the gastrointestinal tract and produces persistent blood levels. The drug is excreted partly in the urine and partly through the intestinal tract, in the feces. The biochemical basis of activity of sulphaquinoxaline as well as other Sulphonamides is their mimicry of {Paraaminobenzoic acid} (PABA) in the folic acid pathways. PABA and Folic acid are particularly important in synthesis of large amounts of nuclear material during development of the coccidial second-generation schizonts. Blockage of PABA and folic acid pathways by sulphonamides prevents proper development of the schizonts. Sulphaquinoxaline causes damage against sporozoites in addition to its anticoccidial effect against schizonts of E. tenella in particular.
SULFAQUINE is indicated for the prophylaxis and treatment of caecal and intestinal coccidiosis in chickens, turkeys as well as intestinal and hepatic coccidiosis in rabbits.
When SULFAQUINE is added to mash, it controls mortality from acute fowl cholera (Pasteurella multocida).
Losses due to fowl typhoid (Salmonella gallinarum) in turkeys can often be reduced by giving SULFAQUINE in the drinking water.
SULFAQUINE is also effective in the treatment of intestinal coccidiosis in rabbits.
Doses and Administration:
Poultry: 1 ml per 2 liters of drinking water for 3 days, one day rest and continue treatment for 2 days more.
Other animals: 0.5 ml per 10 kg of body weight for 3 – 5 days.
Withdrawal period:
Meat: 10 days.
Contraindications and Precautions:
In replacement layer birds, medication should be stopped at least 28 days before birds come into laying.
Store in a dark place at a temperature below 30 ºC.
100, 500 ml and 1 liter plastic bottles.