A water Soluble Powder for Oral Use

Composition : Each 1 gm contains :
Sulphadimidine Sodium 300 mg
The mode of action of sulphonamides, of which Sulphadimidine may be taken as a typical example, are bacteriostatic rather than bactericidal and considered to be due to the similarity of their chemical structure to that of Para-amino benzoic acid (PABA), a substance that is essential for the synthesis of folic acid by the bacterial cell which unlike mammalian cells is unable to absorb preformed foliate, sulphonamide competitively inhibits the responsible enzyme which then becomes in-capable of its normal function.
Sulphonamides acts against many species of bacteria including Gram- positive and Gram-negative.
Sulphamethazine is highly effective against a wide range of bacterial, protozoal and certain riketitsial organisms. It is particularly useful in cases of septicemia, pneumonia and enteritis in calves and lambs and also diseases caused by Salmonella Pasteurella and, as well as, in the treatment of caecal and intestinal coccidiosis, coryza and fowl cholera in poultry.
Dosage and administration:
By oral route
Poultry: 60-80 g per 200 liters of drinking water for 3-5 days.
Calves and lambs: first day: 3 g per 10kg b.wt. then 1.5g per 10kg b.wt. for 3-5 days.
Withdrawal period:
Meat: Poultry: 14 days.
Calves & lambs: 10 days.
Eggs: Should not be use in birds producing egg for human consumption.
Store in a dark place at a temperature 30C.
100, 500 g and 1kg aluminum foil bag.