A water Soluble Powder for Oral Use
Composition: Each 1 kg. contains:
Sulphadimidine sodium 125 g.
Sulphathiazole sodium 125 g.
Sulphadiazine sodium 125 g.
The mode of action of sulphonamides are bacteriostatic rather than bactericidal and considered to be due to the similarity of their chemical structure to that of Para-amino benzoic acid (PABA), a substance that is essential for the synthesis of folic acid by the bacterial cell which unlike mammalian cells is unable to absorb preformed foliate, sulphonamide competitively inhibits the responsible enzyme which then becomes in-capable of its normal function.
Sulphonamides acts against many species of bacteria including Gram- positive and Gram-negative.
The three active ingredients of the preparation TRI SULPHA are the most active of the systemic sulphonamides. They are mainly active against Gram-positive bacteria, some Gram-negative organisms, a few rickettsia, and some protozoa. They are active against Streptococci, Staphylococci, E. coli, Salmonella, Pasterurella, and have some actions against pseudomonas, proteus and Clostridium spp. They are also very effective in the treatment of coccidiosis.
TRI SULPHA is indicated mainly for the prevention and treatment of bacterial infections including: pneumonia, septicaemia, enteritis, foot rot and diarrhea in large animals, and coryza and coccidiosis in poultry.
Dosage and Administration:
Poultry: 100 g per 200 liters of drinking water for 3 days. Suspend treatment for 2 days, then resume for another 2 days in acute cases.
Large animals: 8-10 g per 50 kg body weight for 3 days, via drinking water. Suspend treatment for 2 days, then resume for another 2 days in acute cases.
Meat: 7 days.
Eggs: Should not be use in birds producing egg for human consumption.
Contra-indications and warnings:
Avoid long treatment with TRI SULPHA in parent stock.
Treatment should not exceed 5 days.
Store in a dark place at a temperature below 30C.
100, 500 g and 1kg aluminum foil bag.
FOR VETERINARY USE ONLY