Composition: Each 1 ml contains:
Levamisole Hydrachloride 118 g.
Levamisole Hydrochloride (Levamisole avico Liquid) is a highly acceptable antinematodal drug because of its broad range of activity in a large number of hosts (sheep, cattle, horse, chicken, dog, and cat). Major advantages of levamisole are that it is effective against nematodes of the lungs and GI tract .
Mode of Action Levamisole hydrochloride has a paralyzing action on nematodes. The paralysis is due to sustained muscle contraction. Levamisole acts as a ganglion stimulant (cholinomimetic). This conclusion is supported by the fact that levamisole-induced contractions of Ascaris suum are blocked by the autonomic ganglion blocking agent's mecamylamine and pempidine.
LEVAMISOLE AVICO is for the treatment of diseases pulmonary and gastrointestinal caused by nematodes sensitive to levamisole, both adult and larvae.
Levamisole has a wide spectrum effect against round worms which infect stomach, omasum, GI tract and lungs of cattle, sheep and goats, also against Ascaridia galli and Heterakis gallinae of poultry.
LEVAMISOLE AVICO affects adult and immature worms and restores immunity which was affected by chronic diseases. Recent studies proved that levamisole improves immunity and can be used to increase immune response in cases of Gumboro disease, chronic disease and vaccination with varal vaccines. Levamisole is levo isomer of Tertamisole and considered to be more safe.
Dosage and administration:
Cattle & Sheep: by single dose of 1 ml per 15 kg body weight, to be given by mouth.
Poultry: 0.2 ml per 1 kg body weight through drinking water for 12 hours. Same dose should be repeated after 21 days.
Contra-indications and warnings:
Animals should not be treated simultaneously with products containing organophosphorous compounds or diethylcarbamazine citrate, neither should such compounds be used within 14 days after treatment. At the therapeutic level, it has no adverse effect on birds or on the hatchability and fertility o their eggs.
Careful estimation of body weight must be made. At the normal dose levels, animals, rarely, show any side effects. The effects of over dosage are transient and include head shaking, salivation and slight muscle tremors; these are likely observed in cattle than in sheep.
Meat: 3 days.
Milk: 24 hours
Store in a dark place at a temperature below 30C.
100, 500 ml and 1 liter plastic bottles.
FOR VETERINARY USE ONLY